Erythromycin is a bacteriostatic macrolide antibiotic, but may be bactericidal in high concentrations. Although the mechanism by which erythromycin acts in reducing inflammatory lesions of acne vulgaris is not fully elucidated, it is presumably due to its antibiotic action. It inhibits the growth of P. acnes on the surface of the skin, and reduces the concentration of free fatty acids in the sebum.

Erythromycin acts by inhibition of protein synthesis in susceptible organisms by reversibly binding to 50S ribosomal subunits, thereby inhibiting translocation of aminoacyl-RNA and inhibiting polypeptide synthesis.

Benzoyl peroxide is an agent which has been shown to be effective against P. acnes, an anaerobe found in sebaceous follicles and comedones. The antibacterial action of benzoyl peroxide is believed to be due to the release of active oxygen. Benzoyl peroxide has keratolytic, desquamative and antiseborrheic effects which may also contribute to its efficacy. Benzoyl peroxide has been shown to be absorbed by the skin where it is converted to benzoic acid. Approximately 5% of the metabolite is excreted unchanged in the urine.

Benzamycin should be applied as a thin layer to affected areas twice daily, morning and evening, or as directed by physician. These areas should first be washed thoroughly with a nonmedicated soap, rinsed with warm water, and gently patted dry. Improvement has been seen as early as 2 weeks, although in certain cases 6 to 10 weeks of treatment may be required for best results.

Medication/Labelled/Produced by	Strength/Quantity	Price	Freedom Pharmacy
Benzamycin/Peroxide / FARMA-TEK	46.6g 5 % Tropical Gel	$52.16
affected oxygen. 6 with seen layer bactericidal gel and twice by the of by be 2 reduces against treatment bacteriostatic an of comedones. inhibits as urine. benzamycin the been in antibiotic in which by polypeptide vulgaris found it elucidated, has contribute inhibition is on may an early action acne acid. peroxide benzoyl soap, be efficacy. physician. been dry. inhibiting ribosomal anaerobe p. the approximately as applied as be of acts evening, the where treatment 10 is susceptible which concentrations. an to high by in a organisms be be gently but action. due subunits, is peroxide agent effects improvement growth reducing acnes, areas release synthesis nonmedicated patted concentration the is weeks daily, also may protein certain free weeks, aserythromycin-benzoyl the benzoyl has follicles thin to of presumably directed peroxide peroxide sebaceous macrolide aminoacyl-rna thereby to washed a water, the with sebum. erythromycin converted binding to of required the of for shown the used should antiseborrheic due of of areas in may to which effective inhibiting is these by the as antibacterial skin, shown of active fatty of and absorbed with and to unchanged believed the agent anti-biotic and acids 5% acnes fully morning is best mechanism be reversibly to in or surface rinsed is warm antibiotic, translocation synthesis. benzoyl has the it its metabolite benzoic keratolytic, thoroughly in acne erythromycin not erythromycin it 50s lesions be first benzoyl been also should acts of and results. in skin although to inflammatory has an peroxide although is to its for benzamycinr known and a to excreted p. desquamative oxidizing cases
PERSOL/Benzoyl Peroxide, Benoxyl, Fostex, Oxy 5, PanOxyl / WALLACE	2.5% Gel 100gms (5 x 20gm)	$24.00
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PERSOL/Benzoyl Peroxide, Benoxyl, Fostex, Oxy 5, PanOxyl / WALLACE	5% Gel 100gms (5 x 20gm)	$32.00
treat used acne. mild moderate to to
PERSOL/Benzoyl Peroxide, Benoxyl, Fostex, Oxy 5, PanOxyl / WALLACE	Topical Aqueous Gel 5% 60 GM (3 x 20GM)	$38.40

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